BOLETÍN ELECTRÓNICO CIENTÍFICO
DEL NODO BRASILERO
DE INVESTIGADORES COLOMBIANOS
Número 2(Artículo 08), 2000
TÍTULO
Plasma biochemical profile in dogs with gastrointestinal disorders
TIPO: Trabajo publicado en Arq. Fac. Vet. UFRGS v.27, n.2: 80-86. 1999
AUTOR: Félix H. D. González felixgon@ufrgs.br, Vanessa M. Möller and Virgínia de Carvalho
IDIOMA: Inglés
DIRECCIÓN PARA CONTACTO
Clinical Pathology Department, Faculty of Veterinary, Federal University of Rio Grande do Sul (UFRGS)
Av. Bento Gonçalves 9090. Porto Alegre - RS - Brazil. 91.540-000
PALABRAS CLAVE: Clinical Biochemistry, Canine Medicine, Gastrointestinal Disorders
RESUMEN
Biochemical plasma profiles have been used worldwide in Veterinary Medicine to provide important information regarding the clinical status of an animal. A study of the variations of biochemical profiles should include its own normal reference ranges for the specific population [1], because there are important variations in a species due to breed, sex, climate, nutritional regime, age or physiological status of the animal [2]. There are few studies in Brazil concerning the study of variations in the plasma biochemical profiles in healthy and diseased dogs [3] [4]. The aim of the present work is to study the variations of some analyses of the plasma biochemical profile in dogs suffering from gastrointestinal disease, one of the most common disorder observed in our veterinary hospital, located in the southern region of Brazil. There were studied the variations in some blood chemistry parameters in 30 dogs. Symptoms observed were basically diarrhea, vomiting, apathy, inappetence, fever, abdominal pain, intestinal hemorrhage and dehydration. Eighty percent of the dogs were one year-old or less. Normal reference values from our own laboratory [5] were used to compare the profiles, which included: glucose, cholesterol, total protein, albumin, globulins, urea, creatinin, bilirubin, alanine aminotransferase (ALT), alkaline phosphatase (ALP), calcium, phosphorus, magnesium, packed cell volume (PCV) and hemoglobin. The results showed a clear hypoproteinemia, from both albumin and globulins origin, a tendency for low glycemia and high cholesterolemia generated by a negative energy balance. Creatinin values were bellow reference range in 65.5% of the dogs. Levels of this metabolite can decreased in a severe protein deficiency [6]. The enzymatic activity of alkaline phosphatase was abnormally elevated in 32.1% of the cases. This enzyme can be increased due to tissue injury caused by enteritis [7]. A diminished renal filtration was observed, indicated by high levels of phosphorus and urea. PCV values were below lower limits in 43.3% and hemoglobin in 40% of the cases, illustrating clear cases of anemia, which is accentuated by protein and blood losses in the intestine and also from malnutrition or inflammation derived from enteric disorder [8]. Finally, bilirubin values were above reference values in 26% of the cases, which could be illustrating a hepatic compromise of the disease.
BIBLIOGRAPHY
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[8] SHERDING, R.G. Diseases of Small Bowel. In: ETTINGER, S.J. (Ed.) Textbook of Veterinary Internal Medicine. Vol.2. Philadelphia: W.B. Saunders Co. 1989.
BECNBIC,2(08)2000